High Purity 99.0%min. Linaclotide Lyophilized powder Peptide CAS NO.:851199-59-2 Research Chemical
Product Information:
INCI Name: Linaclotide
Cas No: 851199-59-2
Molucular Formula: : C59H79N15O21S6
Molecular Weight: 1526.74
Sequence:Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr(Cys1Cys6,Cys2Cys10, Cys5Cys13 bridge)
Purity: >99%
Source: Synthetic
Grade: Cosmetic
Stability: Stable
Solubility: Slightly soluble in water
Formulation: Available for your reference, please contact us
MSDS and COA: Available for your reference, please contact us
Appearance: White Lyophilized powder
Storage:After reconstitution store at 2°C - 8°C
Description:
Linaclotide is an administered, peptide agonist of guanylate cyclase 2C for the treatment of irritable bowel syndrome. Chemically, it is a heterodetic cyclic peptide and consists of fourteen amino acids.
Linaclotide is used to treat certain types of bowel problems (irritable bowel syndrome with constipation, chronic idiopathic constipation). It works by increasing fluid in your intestines and helping speed up movement of food through the gut. Linaclotide may improve stool texture and lessen symptoms such as bloating, abdominal pain/discomfort, straining, and feelings of incomplete bowel movements. FDA approved on August 30, 2012.
Linaclotide reduces activation of colonic sensory neurons, reducing pain; and activates colonic motor neurons, which increases smooth muscle contraction and thus promotes bowel movements. It was approved by the FDA in August 2012 for the treatment of chronic idiopathic constipation and constipation predominant irritable bowel syndrome (IBS-C) in adults.
Clarify:
Our peptides is just for Reseach&Lab use,not used on Human body.
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